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Why is Delta more dangerous and harder to stop than other strains?

First of all, Delta is more infectious than other variants of COVID-19. Also, it is more capable of evading immunity generated by vaccination or previous natural infection.

Now, the exact reason behind this is not known, but scientists assume that there could be a combination of factors leading to this, like: faster replication which leads to significantly higher concentrations in the upper airways, greater quantities expelled by infected individuals, viral particles are better at latching on the ACE2 receptor which is an enzyme the virus uses to infect cells, and a greater efficiency at causing infection.

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